Description

2,3-Estrone o-Quinone is a specialized steroid-derived quinone compound of significant interest in biochemical and pharmaceutical research. This compound serves as a critical intermediate and reference standard in the study of estrogen metabolism and oxidative pathways. It is primarily utilized by research institutions and pharmaceutical development laboratories focused on endocrinology, cancer research, and the synthesis of novel therapeutic agents.

Application

• Biochemical Research Intermediate: A key compound for investigating the metabolic pathways and oxidative transformation of estrone and related estrogens.
• Pharmaceutical Reference Standard: Used as a high-purity analytical standard in method development and quality control for steroid-based drug substances.
• Endocrinology Studies: Employed in research to understand the biological activity and potential effects of estrogen metabolites.
• Organic Synthesis Building Block: Serves as a precursor or intermediate in the synthesis of more complex steroid derivatives and analogs for biological screening.
• Academic Research: Utilized in university and institutional labs for fundamental studies in steroid chemistry and oxidative stress mechanisms.

Basic Information

Product Name	2,3-Estrone o-Quinone
CAS No.	40551-33-5
Molecular Formula	C18H20O3
Molecular Weight	284.35 g/mol
Synonyms	2,3-Estrone quinone; Estrone-2,3-quinone; 2,3-Dioxo-1,3,5(10)-estratrien-17-one; 1,3,5(10)-Estratrien-17-one, 2,3-dihydroxy-; 2,3-Dihydroxyestra-1,3,5(10)-trien-17-one quinone; Estrone 2,3-quinone; 2,3-Estra-1,3,5(10)-triene-17-one quinone
EINECS	Contact for details

Quality Control

Our 2,3-Estrone o-Quinone is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.