Description

Ribavirin Amidine CAS NO 40372-00-7 is a key chemical intermediate, specifically the amidine derivative of the broad-spectrum antiviral nucleoside Ribavirin. This compound matters for its critical role in the synthesis and research of antiviral pharmaceuticals, particularly those targeting RNA viruses. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antiviral drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Ribavirin and its prodrugs or analogs.
• Antiviral Research: Used in biochemical and pharmacological studies to investigate mechanisms of action and structure-activity relationships (SAR).
• Process Chemistry: Serves as a key intermediate in the scale-up and optimization of antiviral active pharmaceutical ingredient (API) manufacturing processes.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and method development for related pharmaceutical products.
• Nucleoside Chemistry: A valuable reagent for the synthesis of modified nucleosides with potential therapeutic applications.

Basic Information

Product Name	Ribavirin Amidine
CAS No.	40372-00-7
Molecular Formula	C8H12N4O5
Molecular Weight	244.21 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-1H-1,2,4-triazole-3-carboxamidine; 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamidine; Ribavirin 3-Carboxamidine; Virazole Amidine; 3-Carbamimidoyl-1-β-D-ribofuranosyl-1H-1,2,4-triazole; 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide
EINECS	Contact for details

Quality Control

Our Ribavirin Amidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.