Description

Glycerol, [2-14C] is a carbon-14 labeled isotopologue of glycerol, a fundamental trihydric alcohol, with the radiolabel specifically positioned at the second carbon atom. This compound is essential for advanced metabolic and biochemical tracer studies, providing a critical tool for tracking carbon atom fate and flux in complex biological systems. It is primarily required by researchers and quality control laboratories in the pharmaceutical, biotechnology, and agrochemical industries for drug metabolism studies, pathway elucidation, and environmental fate analysis.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study glycolysis, gluconeogenesis, and triglyceride synthesis in vivo and in vitro.
• Pharmaceutical R&D: Critical for absorption, distribution, metabolism, and excretion (ADME) studies of new drug candidates to understand their metabolic fate.
• Biochemical Research: Employed in enzymatic assays and studies of lipid metabolism to quantify reaction rates and identify intermediates.
• Environmental Science: Applied in research on the biodegradation pathways of glycerol-based compounds in ecosystems.
• Diagnostic Agent Development: Serves as a precursor in the synthesis of labeled compounds for potential use in diagnostic imaging and assays.
• Quality Control & Reference Standard: Used as an internal standard in mass spectrometry and other analytical techniques for accurate quantification.

Basic Information

Product Name	Glycerol, [2-14C]
CAS No.	4819-42-5
Molecular Formula	C3H814CO3
Molecular Weight	94.09 g/mol (for unlabeled); Contact for specific activity details.
Synonyms	[2-14C]Glycerol; 1,2,3-Propanetriol-2-14C; Glycerin-2-14C; Glyceritol-2-14C; 2-14C-Glycerol; Radiolabeled Glycerol; Carbon-14 Labeled Glycerol; Trihydroxypropane-2-14C
EINECS	Contact for details

Quality Control

Every batch of Glycerol, [2-14C] is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Comprehensive analytical testing, including HPLC with radiometric detection, is performed to confirm radiochemical purity and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific activity, purity, and solvent information. Our quality commitment supports compliance with the rigorous standards required for preclinical and clinical research.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability. This product is hygroscopic (moisture-sensitive); ensure containers are sealed properly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider conditions as advised in the material-specific handling sheet.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR/NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent	Specified on label (e.g., Water, Ethanol)
Concentration	Specified on label (mCi/mL or µCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.