Description

4-Bromo-2,3,5,6-Tetrafluorobenzoic Acid is a highly functionalized aromatic building block characterized by its unique combination of bromine and fluorine substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for applications in medicinal chemistry, ligand synthesis, and the development of liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides where the fluorinated benzoic acid moiety is required.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-based ligands and core structures in electronic display and lighting materials.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymers to enhance thermal stability, chemical resistance, and surface properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	4-Bromo-2,3,5,6-Tetrafluorobenzoic Acid
CAS No.	4707-24-8
Molecular Formula	C7HBrF4O2
Molecular Weight	264.98 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-bromobenzoic Acid; Benzoic acid, 4-bromo-2,3,5,6-tetrafluoro-; 4-Bromo-2,3,5,6-tetrafluorobenzoic acid; TFBBA; Tetrafluorobromobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3,5,6-Tetrafluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.