Description

Methyl 4-Bromo-2,3,5,6-Tetrafluorobenzoate is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its unique combination of bromine and fluorine substituents, which make it a versatile intermediate for introducing specific functional groups and modifying electronic properties in target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the tetrafluorobenzene moiety contributes to product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs), where fluorine atoms help tune electronic properties and stability.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi), enabling the construction of complex biaryl structures.
• Functional Polymer Monomer: Employed in the creation of specialty polymers with tailored properties such as chemical resistance, low dielectric constant, or specific optical characteristics.
• Chemical Research & Development: A valuable tool for medicinal chemistry and material science research, facilitating structure-activity relationship (SAR) studies and the exploration of new chemical spaces.

Basic Information

Product Name	Methyl 4-Bromo-2,3,5,6-Tetrafluorobenzoate
CAS No.	4707-23-7
Molecular Formula	C8H3BrF4O2
Molecular Weight	287.01 g/mol
Synonyms	4-Bromo-2,3,5,6-tetrafluorobenzoic acid methyl ester; Methyl 4-bromotetrafluorobenzoate; Benzoic acid, 4-bromo-2,3,5,6-tetrafluoro-, methyl ester; Methyl perfluorobromobenzoate; 2,3,5,6-Tetrafluoro-4-bromobenzoic acid methyl ester; Methyl 2,3,5,6-tetrafluoro-4-bromobenzoate; 4-Bromo-2,3,5,6-tetrafluorobenzoic acid, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2,3,5,6-Tetrafluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.