Description

Methyl 2,3,5,6-Tetrafluorobenzoate is a high-purity fluorinated aromatic ester, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzoate ring, which significantly influences the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials where fluorination is a key design strategy.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where fluorine atoms enhance biological activity, metabolic stability, and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated liquid crystal compounds and organic semiconductors, contributing to improved display performance and device stability.
• Polymer & Material Science: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing material properties such as chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution reactions to construct complex, polyfluorinated aromatic systems.

Basic Information

Product Name	Methyl 2,3,5,6-Tetrafluorobenzoate
CAS No.	4707-12-4
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	2,3,5,6-Tetrafluorobenzoic Acid Methyl Ester; Methyl 2,3,5,6-Tetrafluorobenzenecarboxylate; Benzoic Acid, 2,3,5,6-Tetrafluoro-, Methyl Ester; Methyl Perfluoroterephthalate (common misnomer); MTTFB; Methyl Tetrafluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,3,5,6-Tetrafluorobenzoate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.