Description

2-Biphenylboronic Acid is a versatile organoboron compound widely used as a key building block in modern synthetic chemistry. Its primary value lies in its role as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is utilized in the development of active pharmaceutical ingredients (APIs), advanced polymers, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific biaryl motifs.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis and other organometallic complexes.
• Academic & Industrial R&D: A fundamental reagent in chemical research laboratories for method development and exploring new synthetic pathways.
• Fine Chemical Production: Integral to the manufacture of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	2-Biphenylboronic Acid
CAS No.	4688-76-0
Molecular Formula	C12H11BO2
Molecular Weight	198.03 g/mol
Synonyms	[2-(Phenyl)phenyl]boronic acid; 2-Phenylbenzeneboronic acid; o-Phenylbenzeneboronic acid; Biphenyl-2-ylboronic acid; (1,1'-Biphenyl)-2-ylboronic acid; 2-Biphenylylboronic acid; 2-Boronobiphenyl; (2-Biphenylyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Biphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We can supply material compliant with various pharmacopeial and research-grade specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Melting Point	~150-155°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.