Description

cis-1,2-Indane Diol is a versatile chiral building block and synthetic intermediate of significant importance in fine chemical synthesis. Its value lies in its rigid, fused bicyclic structure and the presence of two adjacent hydroxyl groups in a cis configuration, enabling precise stereochemical control in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, neurological agents, and other bioactive molecules.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, crucial for efficient enantioselective reactions.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polymers with unique thermal and mechanical properties.
• Flavor and Fragrance Industry: Intermediate in the synthesis of complex aroma chemicals and musk compounds.
• Academic and R&D: Valuable reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	cis-1,2-Indane Diol
CAS No.	4647-42-1
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	(1R,2S)-1,2-Dihydroxyindane; (1S,2R)-1,2-Dihydroxyindane; cis-1,2-Dihydroxyindane; 1,2-Indandiol (cis-); Indane-1,2-diol (cis-); (1R,2S)-1,2-Indanediol; (1S,2R)-1,2-Indanediol; 1,2-Dihydroxy-2,3-dihydro-1H-indene
EINECS	Contact for details

Quality Control

Our cis-1,2-Indane Diol is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.