Description

Propionic Acid, Sodium Salt, [1-14C]- is a carbon-14 labeled isotopologue of sodium propionate, a widely used preservative and antifungal agent. This radiolabeled compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to track the fate of propionate in complex biological and chemical systems. It is a critical tool for scientists in the pharmaceutical, agrochemical, and food safety industries who require definitive data on compound absorption, distribution, metabolism, and excretion (ADME).

Application

• Metabolic Pathway Tracing: Used as a radiotracer to study the metabolism of propionic acid and its salts in vivo and in vitro.
• Pharmaceutical ADME Studies: Critical for investigating the absorption, distribution, metabolism, and excretion profiles of propionate-based drug candidates.
• Biochemical Research: Employed in enzymatic studies to elucidate mechanisms involving propionyl-CoA and related metabolic cycles.
• Agrochemical Research: Facilitates environmental fate studies and residue analysis of propionate-based fungicides and preservatives.
• Microbial Fermentation Studies: Tracks propionate utilization and production in microbiological and industrial fermentation processes.
• Food Science Research: Enables studies on the efficacy and breakdown of sodium propionate as a food preservative.

Basic Information

Product Name	Propionic Acid, Sodium Salt, [1-14C]-
CAS No.	4561-17-5
Molecular Formula	C14CH5NaO2 or C3H5NaO2 (labeled)
Molecular Weight	~96.06 g/mol (exact mass depends on specific activity)
Synonyms	Sodium [1-14C]propionate; [1-14C]Propionic acid sodium salt; Sodium Propionate-1-14C; NSC 4561; Propanoic acid, sodium salt (1-14C); E281 (labeled variant)
EINECS	Contact for details

Quality Control

Every batch of Propionic Acid, Sodium Salt, [1-14C]- is manufactured and analyzed under strict quality systems to ensure high chemical and radiochemical purity. Our quality commitment includes verification of specific activity, radiochemical identity, and chemical purity using techniques such as HPLC and radio-HPLC. A comprehensive Certificate of Analysis (COA) detailing all specifications, including radionuclidic purity and analytical chromatograms, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container in a cool, dry, and well-ventilated area dedicated for radiochemicals. Follow all applicable local and international regulations for the storage and handling of radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solubility	Soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.