Description

Foscarnet CAS NO 4428-95-9 is an antiviral compound, specifically a pyrophosphate analog, that acts as a selective inhibitor of viral DNA polymerases and reverse transcriptases. Its primary commercial value lies in its critical role as an active pharmaceutical ingredient (API) for the formulation of antiviral medications. This product is essential for pharmaceutical manufacturers and research institutions developing treatments for herpesvirus infections, including cytomegalovirus (CMV) retinitis in immunocompromised patients, and for investigating novel antiviral therapies.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable antiviral drugs for treating CMV retinitis and acyclovir-resistant herpes simplex virus (HSV) infections.
• Antiviral Research: A key reference standard and tool compound in virology research for studying viral replication mechanisms and screening new antiviral agents.
• Biochemical Studies: Used in enzymology to investigate the structure and function of viral DNA polymerases and reverse transcriptases.
• Veterinary Medicine: Potential application in developing antiviral treatments for animal herpesviruses.

Basic Information

Product Name	Foscarnet
CAS No.	4428-95-9
Molecular Formula	CH5O5P
Molecular Weight	128.02 g/mol
Synonyms	Trisodium phosphonoformate; Phosphonoformic acid, trisodium salt; Foscarnet sodium; Foscavir; PFA; Trisodium carboxyphosphate; (Phosphonooxy)formic acid trisodium salt; NSC 342834
EINECS	224-599-6

Quality Control

Our Foscarnet is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results against relevant specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Microbial Limits	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.