Description

Glutamic Acid, Dl-, [1-14C] CAS NO 4219-82-3 is a carbon-14 labeled variant of the amino acid glutamic acid, specifically radiolabeled at the 1-carbon position. This compound is a critical tool for advanced metabolic and biochemical research, enabling precise tracking and quantification in complex biological systems. It is essential for researchers and scientists in pharmaceutical development, agricultural chemistry, and life sciences who require high-specific-activity tracers for autoradiography, ADME studies, and pathway analysis.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the biosynthesis and catabolism of glutamic acid and related compounds like glutamine, proline, and arginine.
• Pharmaceutical ADME Studies: Critical for Absorption, Distribution, Metabolism, and Excretion (ADME) research of drug candidates that interact with glutamate receptors or pathways.
• Neurochemical Research: Enables investigation into the role of glutamate as a primary excitatory neurotransmitter in the central nervous system.
• Agricultural Biochemistry: Applied in studies of nitrogen metabolism and amino acid synthesis in plants and crops.
• Microbial Fermentation Analysis: Used to trace and optimize glutamic acid production in industrial fermentation processes, such as those for monosodium glutamate (MSG).
• Biomarker Development: Serves as a precursor in the synthesis of radiolabeled biomarkers for diagnostic imaging and research.

Basic Information

Product Name	Glutamic Acid, Dl-, [1-14C]
CAS No.	4219-82-3
Molecular Formula	C5H914CNO4 *
Molecular Weight	Contact for details
Synonyms	DL-Glutamic acid-1-14C
(±)-Glutamic acid-1-14C
1-14C-Glutamic acid
Glutamic acid (U-14C) (common mis-assignment for specific position)
2-Aminopentanedioic acid-1-14C
[1-14C]DL-Glutamic acid
Racemic glutamic acid-1-14C
EINECS	Contact for details

* Formula indicates 14C at the 1-carbon (carboxyl) position.

Quality Control

Every batch of Glutamic Acid, Dl-, [1-14C] is manufactured and analyzed under strict quality systems to ensure high radiochemical purity and specific activity. Our quality protocols are designed to meet the stringent requirements of research and regulatory applications. Certificates of Analysis (COA) are provided with each shipment, detailing critical parameters such as radiochemical purity, chemical purity, specific activity, and solvent composition. We support compliance with cGMP and GLP standards for advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container sealed under an inert atmosphere in a dedicated freezer. Follow all applicable radiation safety guidelines for handling and storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (Radio-HPLC/TLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (for solutions)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.