Description

3-Bromo-5-Fluoro-2-Hydroxybenzoic Acid is a versatile halogenated salicylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents on the aromatic ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the bromo and fluoro groups can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the creation of advanced organic materials, such as liquid crystals or organic semiconductors, where its substitution pattern can influence electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems due to its modifiable carboxylic acid and hydroxyl groups.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Hydroxybenzoic Acid
CAS No.	4180-42-1
Molecular Formula	C7H4BrFO3
Molecular Weight	235.01 g/mol
Synonyms	5-Fluoro-3-bromosalicylic acid; 2-Hydroxy-3-bromo-5-fluorobenzoic acid; 3-Bromo-5-fluorosalicylic acid; Benzoic acid, 3-bromo-5-fluoro-2-hydroxy-; 3-Br-5-F-2-OH-BA; 3-Bromo-5-fluoro-2-hydroxybenzoic acid; 4180-42-1 (CAS)
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-5-Fluoro-2-Hydroxybenzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure consistency and reliability for your synthetic workflows. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.