Description

[2S-(2Alpha,5Alpha,6Beta)]-3,3-Dimethyl-7-Oxo-6-(Phenylacetamido)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid 4-Oxide is a key sulfoxide derivative and a critical intermediate in the synthesis of advanced β-lactam antibiotics. This compound matters for its role in producing high-purity, potent pharmaceutical actives, offering supply chain reliability for manufacturers. It is primarily needed by pharmaceutical R&D laboratories, fine chemical producers, and API manufacturers focused on developing next-generation antibacterial therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of penicillin sulfoxide derivatives and other β-lactam antibiotics.
• API (Active Pharmaceutical Ingredient) Synthesis: Used in the production pathway for specific, high-value antibiotic active ingredients.
• Chemical Research & Development: Serves as a reference standard and starting material for novel antibacterial compound discovery in academic and industrial labs.
• Process Chemistry Optimization: Employed in scaling up and refining synthetic routes for antibiotic manufacturing.
• Fine Chemical Production: Supplied to fine chemical companies for further functionalization and sale to the pharmaceutical sector.

Basic Information

Product Name	[2S-(2Alpha,5Alpha,6Beta)]-3,3-Dimethyl-7-Oxo-6-(Phenylacetamido)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid 4-Oxide
CAS No.	4052-54-4
Molecular Formula	C16H18N2O5S
Molecular Weight	350.39 g/mol
Synonyms	Penicillin G Sulfoxide; 6-Phenylacetamidopenicillanic Acid Sulfoxide; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide; Benzylpenicillin Sulfoxide; Penicillin G 1-Oxide; 6-APA Sulfoxide Phenylacetyl Derivative; Phenylacetyl-6-APA Sulfoxide; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, 4-oxide, (2S,5R,6R)-
EINECS	Contact for details

Quality Control

Our [2S-(2Alpha,5Alpha,6Beta)]-3,3-Dimethyl-7-Oxo-6-(Phenylacetamido)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid 4-Oxide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed HPLC, NMR, and IR data are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.