Description

(8Alpha,9R)-10,11-Dihydrocinchonan-9-Ol CAS NO 485-64-3 is a high-purity, stereochemically defined cinchona alkaloid derivative, serving as a critical chiral building block and catalyst in advanced organic synthesis. Its primary value lies in its exceptional utility as a ligand for asymmetric catalysis, enabling the production of enantiomerically pure compounds essential for pharmaceuticals and fine chemicals. This product is indispensable for research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-performance chiral auxiliaries.

Application

• As a chiral ligand in asymmetric synthesis, particularly for phase-transfer catalysis (PTC).
• As a key intermediate in the synthesis of novel pharmaceutical active ingredients (APIs).
• For the development and scale-up of enantioselective manufacturing processes.
• In academic and industrial research for exploring new catalytic reactions.
• As a precursor for the synthesis of other modified cinchona alkaloid catalysts.
• In the preparation of chiral stationary phases for analytical and preparative chromatography.
• For the resolution of racemic mixtures via diastereomeric salt formation or kinetic resolution.

Basic Information

Item	Details
Product Name	(8Alpha,9R)-10,11-Dihydrocinchonan-9-Ol
CAS No.	485-64-3
Molecular Formula	C19H24N2O
Molecular Weight	296.41 g/mol
Synonyms	10,11-Dihydrocinchonidine; (8α,9R)-10,11-Dihydrocinchonan-9-ol; Dihydrocinchonidine; Cinchonan-9-ol, 10,11-dihydro-, (8α,9R)-; (9R)-10,11-Dihydrocinchonan-9-ol; (R)-(+)-10,11-Dihydrocinchonidine; 485-64-3; Dihydrocinchonidine base
EINECS	207-619-7

Quality Control

Our (8Alpha,9R)-10,11-Dihydrocinchonan-9-Ol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.