Description

3-(Trifluoromethyl)Benzoic Acid is a versatile fluorinated aromatic carboxylic acid, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive carboxylic acid functionality, enabling precise molecular modifications. This compound is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity.
• Liquid Crystal & OLED Materials: Acts as a precursor in the synthesis of fluorinated compounds for electronic displays and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Organic Synthesis Reagent: Employed in coupling reactions (e.g., amide formation, esterification) and as a directing group in metal-catalyzed transformations.
• Coordination Chemistry Ligand: Can be used to synthesize metal-organic frameworks (MOFs) and complexes for catalysis.

Basic Information

Product Name	3-(Trifluoromethyl)Benzoic Acid
CAS No.	454-92-2
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	m-(Trifluoromethyl)benzoic acid; 3-Trifluoromethylbenzoic acid; Benzoic acid, 3-(trifluoromethyl)-; α,α,α-Trifluoro-m-toluic acid; m-Trifluoromethylbenzoic acid; 3-Carboxybenzotrifluoride; m-Carboxybenzotrifluoride; 3-TFMBA
EINECS	207-239-6

Quality Control

Our 3-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the highest standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	103 - 107 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.