Description

Ethyl 2-Fluorobenzoate is a versatile fluorinated aromatic ester, a key building block in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom and an ester group onto the benzene ring, enabling precise modifications to molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, ester hydrolysis, and reduction reactions to access a variety of 2-fluorobenzoic acid derivatives.
• Flavor & Fragrance Industry: Potential use in the synthesis of complex aromatic esters for creating specialized scent and flavor profiles.
• Polymer Modification: Can be incorporated into polymer chains to alter physical properties such as solubility, thermal stability, and chemical resistance.

Basic Information

Product Name	Ethyl 2-Fluorobenzoate
CAS No.	443-26-5
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	2-Fluorobenzoic Acid Ethyl Ester; Ethyl o-Fluorobenzoate; Benzoic acid, 2-fluoro-, ethyl ester; o-Fluorobenzoic Acid Ethyl Ester; Ethyl 2-fluorobenzenecarboxylate; NSC 404058; Ethyl 2-Fluorobenzoate
EINECS	207-138-8

Quality Control

Our Ethyl 2-Fluorobenzoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.15 g/mL
Refractive Index (n20/D)	~1.495 - 1.505

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.