Description

5-Fluoro-2-Hydroxybenzoic Acid Ethyl Ester is a versatile fluorinated aromatic ester that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl and an ester group on a fluorinated benzene ring, makes it a valuable intermediate for creating compounds with tailored biological and physical properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce fluorine atoms into complex molecules to modulate their activity, stability, and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances product efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic components in electronic display materials, improving their dielectric and optical properties.
• Organic Synthesis & Chemical Research: Employed as a versatile reagent for introducing the 5-fluoro-2-hydroxybenzoate moiety into more complex molecular architectures in academic and industrial R&D settings.
• Dye & Pigment Intermediate: Utilized in the production of specialized fluorinated dyes and pigments that offer superior lightfastness and color properties.

Basic Information

Product Name	5-Fluoro-2-Hydroxybenzoic Acid Ethyl Ester
CAS No.	443-12-9
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	Ethyl 5-Fluoro-2-hydroxybenzoate; Ethyl 5-Fluorosalicylate; 2-Hydroxy-5-fluorobenzoic Acid Ethyl Ester; 5-Fluorosalicylic Acid Ethyl Ester; 5-Fluoro-2-hydroxybenzoic Acid Ethyl Ester; Salicylic acid, 5-fluoro-, ethyl ester; Benzoic acid, 5-fluoro-2-hydroxy-, ethyl ester
EINECS	207-137-8

Quality Control

Our 5-Fluoro-2-Hydroxybenzoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and IR/NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.