Description

Benzoyl Fluoride, 4-Nitro- (9Ci) CAS NO 403-50-9 is a specialized aromatic fluorination reagent and a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic introduction of both a nitro group and a reactive acyl fluoride moiety, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the nitrobenzoyl fluoride structure imparts specific biological activity.
• Liquid Crystal & OLED Material Precursor: Acts as a building block for creating fluorinated aromatic cores in electronic and display materials.
• Polymer Modification Agent: Employed to introduce nitro-aromatic and fluorinated side chains into polymers to alter physical and chemical properties.
• Cross-Coupling Reactions: Functions as an electrophilic coupling partner in palladium-catalyzed reactions for biaryl formation.
• Peptide Chemistry & Bioconjugation: Utilized for selective acylation reactions in peptide synthesis and protein labeling strategies.

Basic Information

Product Name	Benzoyl Fluoride, 4-Nitro- (9Ci)
CAS No.	403-50-9
Molecular Formula	C7H4FNO3
Molecular Weight	169.11 g/mol
Synonyms	4-Nitrobenzoyl Fluoride; p-Nitrobenzoyl Fluoride; 4-Nitrobenzenecarbonyl Fluoride; NSC 404044; Benzoyl fluoride, 4-nitro-; 4-Nitro-benzoyl fluoride; 4-Nitrobenzoyl fluoride (9CI)
EINECS	206-954-8

Quality Control

Our Benzoyl Fluoride, 4-Nitro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, assay, and impurity profiles. Our quality systems support compliance with cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.