Description

Methyl 4-Fluorobenzoate is a versatile fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of both the fluorine atom and the methyl ester group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the fluorine moiety often improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter physical properties such as thermal stability, chemical resistance, and surface energy.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and hydrolysis/transesterification reactions to access 4-fluorobenzoic acid derivatives.
• Flavor & Fragrance Ingredient Intermediate: Used in the controlled synthesis of complex aromatic esters for specialty chemical applications.

Basic Information

Product Name	Methyl 4-Fluorobenzoate
CAS No.	403-33-8
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	4-Fluorobenzoic Acid Methyl Ester; Methyl p-Fluorobenzoate; p-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 4-fluoro-, methyl ester; Methyl 4-fluorobenzenecarboxylate; Methyl para-fluorobenzoate; M4FB; MFB
EINECS	206-963-7

Quality Control

Our Methyl 4-Fluorobenzoate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC/HPLC)	≥ 98.0% (Standard Grade)
Purity (GC/HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.