Description

2-Fluoro-4-Nitrobenzoic Acid is a versatile aromatic building block characterized by its nitro and fluorine substituents, which confer unique reactivity and electronic properties. This compound is essential for the synthesis of complex molecules, offering a strategic handle for further functionalization in advanced chemical processes. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & Material Science: Serves as a building block for fluorinated liquid crystals and advanced organic electronic materials.
• Organic Synthesis & Research: Employed in academic and industrial R&D for Suzuki coupling, amidation, and other cross-coupling reactions to create complex molecular architectures.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized fluorinated dyes and pigments.

Basic Information

Product Name	2-Fluoro-4-Nitrobenzoic Acid
CAS No.	403-24-7
Molecular Formula	C7H4FNO4
Molecular Weight	185.11 g/mol
Synonyms	4-Nitro-2-fluorobenzoic Acid; 2-Fluoro-4-nitrobenzoic acid; Benzoic acid, 2-fluoro-4-nitro-; 2-Fluoro-4-nitro-benzoic acid; NSC 40399; 4-Nitro-2-fluoro-benzoic acid; 2-Fluoro-4-nitrobenzoic acid, 98+%; 2-Fluoro-4-nitrobenzoic acid (contains varying amounts of Nitrobenzoic Acid)
EINECS	206-945-1

Quality Control

Our 2-Fluoro-4-Nitrobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	164 - 168 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.