Description

3-Fluoro-4-Nitrobenzoic Acid is a versatile aromatic building block characterized by its benzoic acid core substituted with both electron-withdrawing nitro and fluorine groups. This unique structure makes it a critical intermediate for synthesizing more complex molecules in advanced research and industrial chemistry. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic scaffold.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated organic compounds used in electronic displays and lighting.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized dyes and colorants.
• Cross-Coupling Reactions: The carboxylic acid and halogen groups make it a suitable substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.
• Organic Synthesis & Research: A valuable reagent for academic and industrial R&D labs exploring new fluorinated compounds and reaction pathways.

Basic Information

Product Name	3-Fluoro-4-Nitrobenzoic Acid
CAS No.	403-21-4
Molecular Formula	C7H4FNO4
Molecular Weight	185.11 g/mol
Synonyms	4-Nitro-3-fluorobenzoic Acid; 3-Fluoro-4-nitrobenzoic Acid; Benzoic acid, 3-fluoro-4-nitro-; 3-Fluoro-4-nitro-benzoic acid; NSC 404082; 3-F-4-NBA; 3-Fluoro-4-nitrobenzoic acid (ACI); 3-Fluoro-4-nitrobenzoic acid (IUPAC)
EINECS	206-947-8

Quality Control

Our 3-Fluoro-4-Nitrobenzoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	168 - 172 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.