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3-Fluoro-4-Methoxybenzoic Acid CAS NO 403-20-3


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CAS No.:403-20-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Fluoro-4-Methoxybenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both fluorine and methoxy substituents, enables precise modulation of electronic and steric properties in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
  • Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
  • Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
  • Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced thermal stability and chemical resistance.
  • Organic Electronic Materials: Acts as a building block for electron-transport materials and semiconductors in OLED and OFET applications.
  • Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name 3-Fluoro-4-Methoxybenzoic Acid
CAS No. 403-20-3
Molecular Formula C8H7FO3
Molecular Weight 170.14 g/mol
Synonyms 4-Methoxy-3-fluorobenzoic Acid; 3-Fluoro-p-anisic Acid; 3-Fluoro-4-methoxybenzenecarboxylic Acid; Benzoic acid, 3-fluoro-4-methoxy-; 3-Fluoro-4-methoxy-benzoic acid; 3-Fluoro-4-methoxybenzoic acid; 403-20-3; 3-Fluoro-4-methoxybenzoic acid (MFCD00042493)
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Quality Control

Our 3-Fluoro-4-Methoxybenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with complete chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point 158°C - 162°C
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals (as Pb) ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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