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3-Fluoro-4-Methoxybenzoic Acid CAS NO 403-20-3
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CAS No.:403-20-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Fluoro-4-Methoxybenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both fluorine and methoxy substituents, enables precise modulation of electronic and steric properties in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.
Application
- Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
- Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
- Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
- Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced thermal stability and chemical resistance.
- Organic Electronic Materials: Acts as a building block for electron-transport materials and semiconductors in OLED and OFET applications.
- Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems.
Basic Information
| Product Name | 3-Fluoro-4-Methoxybenzoic Acid |
| CAS No. | 403-20-3 |
| Molecular Formula | C8H7FO3 |
| Molecular Weight | 170.14 g/mol |
| Synonyms | 4-Methoxy-3-fluorobenzoic Acid; 3-Fluoro-p-anisic Acid; 3-Fluoro-4-methoxybenzenecarboxylic Acid; Benzoic acid, 3-fluoro-4-methoxy-; 3-Fluoro-4-methoxy-benzoic acid; 3-Fluoro-4-methoxybenzoic acid; 403-20-3; 3-Fluoro-4-methoxybenzoic acid (MFCD00042493) |
| EINECS | Contact for details |
Quality Control
Our 3-Fluoro-4-Methoxybenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with complete chromatographic data are provided for traceability and quality assurance.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Melting Point | 158°C - 162°C |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals (as Pb) | ≤20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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