Description

4-Chloro-3-Fluorobenzoic Acid is a versatile halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where the chloro-fluoro substitution can influence bioactivity.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, contributing to the molecular structure of liquid crystals and organic light-emitting diodes.
• Polymer Modifier: Employed to introduce functional groups into polymer chains, altering physical properties like thermal stability or solubility.
• Organic Synthesis Reagent: Serves as a versatile starting material or coupling partner in various cross-coupling and condensation reactions in fine chemical production.
• Research & Development: Essential for medicinal chemistry and material science research in academic and industrial laboratories exploring new chemical entities.

Basic Information

Product Name	4-Chloro-3-Fluorobenzoic Acid
CAS No.	403-17-8
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	3-Fluoro-4-chlorobenzoic acid; Benzoic acid, 4-chloro-3-fluoro-; 4-Chloro-3-fluorobenzoic acid; 403-17-8; 3-Fluoro-4-chlorobenzoic acid; 4-Chloro-3-fluoro-benzoic acid; 4-Chloro-3-fluorobenzoic acid; 4-Chloro-3-fluorobenzoic acid (9CI)
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	162°C - 168°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.