Description

3-Fluoro-4-Hydroxy-Benzoic Acid Methyl Ester is a fluorinated aromatic ester derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both a fluorine atom and a phenolic hydroxyl group, makes it a critical building block for introducing specific functionalities into target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and advanced materials sectors who require precise chemical modifications to develop new active ingredients or functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated monomers used in the production of high-performance liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or unique surface properties.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and material science labs for structure-activity relationship (SAR) studies and novel compound library synthesis.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that offer enhanced light fastness and color properties.

Basic Information

Product Name	3-Fluoro-4-Hydroxy-Benzoic Acid Methyl Ester
CAS No.	403-01-0
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	Methyl 3-Fluoro-4-hydroxybenzoate; 4-Hydroxy-3-fluorobenzoic Acid Methyl Ester; Benzoic acid, 3-fluoro-4-hydroxy-, methyl ester; Methyl 4-hydroxy-3-fluorobenzoate; 3-Fluoro-4-hydroxy methyl benzoate; 3-Fluoro-4-hydroxybenzoic acid, methyl ester; 403-01-0; Methyl 3-fluoro-4-hydroxybenzoate
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Hydroxy-Benzoic Acid Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.