Description

5-Fluoronicotinic Acid is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a fluorine substituent on the nicotinic acid scaffold, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the development of novel fluorinated polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of natural products and biochemical probes for mechanism-of-action studies.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Fluoronicotinic Acid
CAS No.	402-66-4
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	5-Fluoropyridine-3-carboxylic Acid; 3-Carboxy-5-fluoropyridine; 5-Fluoro-3-pyridinecarboxylic Acid; 5-Fluoronicotinic Acid; Nicotinic Acid, 5-fluoro-; 5-Fluoronicotinsäure (German); Acide 5-fluoronicotinique (French)
EINECS	Contact for details

Quality Control

Our 5-Fluoronicotinic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.