Description

()-Menthyl (S)-1-[(R)-α-Methylbenzyl]Aziridine-2-Carboxylate is a high-value, chiral aziridine derivative used as a sophisticated building block in asymmetric synthesis. Its core value lies in its ability to introduce a rigid, three-membered heterocyclic ring with defined stereochemistry, enabling the construction of complex molecules with high enantiomeric purity. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and advanced chiral catalysts.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Utilized to control stereochemistry in the synthesis of complex organic molecules, including natural products and pharmaceuticals.
• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of novel therapeutic agents, especially those requiring specific three-dimensional architectures.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for enantioselective transformations.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, agrochemicals, and advanced materials where precise stereochemical control is paramount.
• Academic and Industrial R&D: A critical reagent for methodological studies in organic chemistry and process chemistry optimization within R&D laboratories.

Basic Information

Product Name	()-Menthyl (S)-1-[(R)-α-Methylbenzyl]Aziridine-2-Carboxylate
CAS No.	397849-97-7
Molecular Formula	C21H31NO2
Molecular Weight	329.48 g/mol
Synonyms	(1S,2R,5S)-2-Isopropyl-5-methylcyclohexyl (2S)-1-[(1R)-1-phenylethyl]aziridine-2-carboxylate; (-)-Menthyl (S)-1-[(R)-α-Methylbenzyl]aziridine-2-carboxylate; L-Menthyl (S)-1-[(R)-1-Phenylethyl]aziridine-2-carboxylate; Aziridine-2-carboxylic acid, 1-[(1R)-1-phenylethyl]-, (1S,2R,5S)-2-isopropyl-5-methylcyclohexyl ester, (2S)-; Chiral Aziridine Ester; (S)-1-[(R)-1-Phenylethyl]aziridine-2-carboxylic Acid (-)-Menthyl Ester
EINECS	Contact for details

Quality Control

Our ()-Menthyl (S)-1-[(R)-α-Methylbenzyl]Aziridine-2-Carboxylate is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and identity confirmation. We adhere to relevant industry standards for fine chemical manufacturing, and specifications can be aligned with specific research or process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.