Description

R-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene]-2,2'-Diol is a high-value, chiral binaphthol derivative widely recognized as a privileged ligand and catalyst precursor in asymmetric synthesis. Its significance lies in its ability to induce high enantioselectivity in a broad spectrum of organic transformations, enabling the production of optically pure intermediates critical for advanced materials and pharmaceuticals. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-purity chiral auxiliaries to develop novel synthetic routes.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, carbon-carbon bond formation, and oxidation.
• As a precursor for BINOL-based phosphoric acid catalysts used in organocatalysis for enantioselective transformations.
• In the synthesis of pharmaceutical intermediates requiring high optical purity, such as active pharmaceutical ingredients (APIs).
• For the development of asymmetric catalysts used in agrochemical and fragrance manufacturing.
• As a building block for chiral functional materials, including polymers and sensors with specific optical properties.
• In academic and industrial research for exploring new methodologies in stereoselective synthesis.

Basic Information

Product Name	R-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene]-2,2'-Diol
CAS No.	394737-30-5
Molecular Formula	C₃₈H₃₄O₂
Molecular Weight	522.68 g/mol
Synonyms	(R)-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-binaphthalene-2,2'-diol; (R)-3,3'-Di(2,4,6-Trimethylphenyl)-1,1'-binaphthyl-2,2'-diol; (R)-3,3'-Di(2,4,6-Trimethylphenyl)-BINOL; (R)-3,3'-Di(2,4,6-Trimethylphenyl)-2,2'-Dihydroxy-1,1'-binaphthyl; (R)-3,3'-Di(2,4,6-Trimethylphenyl)-1,1'-Bi-2-naphthol; (R)-3,3'-Di(2,4,6-Trimethylphenyl)-BINOL; (R)-3,3'-Di(2,4,6-Trimethylphenyl)-H8-BINOL (common misnomer); R-3,3'-Di(2,4,6-Trimethylphenyl)-BINOL
EINECS	Contact for details

Quality Control

Our R-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene]-2,2'-Diol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to meet the exacting standards required for asymmetric synthesis. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and chiral integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.