Description

Boceprevir is a potent and selective small-molecule inhibitor of the hepatitis C virus (HCV) NS3/4A serine protease. This compound matters as a key intermediate and reference standard in the research and development of antiviral therapeutics targeting HCV genotypes. Pharmaceutical R&D laboratories and fine chemical manufacturers require high-purity Boceprevir CAS NO 394730-60-0 for synthesis, analytical method development, and biological activity studies.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel antiviral drug candidates targeting the HCV protease.
• Reference Standard: Used in analytical laboratories for method validation, quality control, and impurity profiling of active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a tool compound in virology studies to investigate HCV replication mechanisms and protease inhibition kinetics.
• Process Development: Employed in scaling up and optimizing synthetic routes for antiviral drug manufacturing.
• Formulation Studies: Used in pre-formulation research to assess stability and compatibility in potential drug product matrices.

Basic Information

Product Name	Boceprevir
CAS No.	394730-60-0
Molecular Formula	C₂₇H₄₅N₅O₅
Molecular Weight	519.68 g/mol
Synonyms	(1R,2S,5S)-N-[4-Amino-1-cyclobutyl-3,4-dioxobutan-2-yl]-3-[(2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide; SCH 503034; VICTRELIS (Brand Name); HCV NS3 Protease Inhibitor
EINECS	Contact for details

Quality Control

Our Boceprevir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.