Description

Benzenemethanol,-(Aminomethyl)-3,4-Dichloro-, (S)- is a chiral, substituted benzylamine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its specific stereochemistry and functional groups into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where its dichloro-substituted aromatic ring provides specific bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the enantioselectivity of chemical reactions.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Benzenemethanol,-(Aminomethyl)-3,4-Dichloro-, (S)-
CAS No.	390406-08-3
Molecular Formula	C8H9Cl2NO
Molecular Weight	206.07 g/mol
Synonyms	(S)-2-Amino-1-(3,4-dichlorophenyl)ethanol; (S)-(-)-2-Amino-1-(3,4-dichlorophenyl)ethanol; (S)-1-(3,4-Dichlorophenyl)-2-aminoethanol; (S)-3,4-Dichloro-α-(aminomethyl)benzyl alcohol; (S)-Norchlorpheniramine alcohol; (S)-Aminomethyl(3,4-dichlorophenyl)methanol; (S)-2-Amino-1-(3,4-dichlorophenyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our Benzenemethanol,-(Aminomethyl)-3,4-Dichloro-, (S)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.