Description

(R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is a high-value, enantiomerically pure binaphthyl derivative that serves as a critical chiral building block and ligand precursor in advanced organic synthesis. Its core value lies in its ability to impart axial chirality and steric bulk, enabling the development of highly selective catalytic systems and complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require sophisticated intermediates for asymmetric synthesis and chiral resolution processes.

Application

• Asymmetric Catalysis: As a precursor for chiral phosphine or diamine ligands used in enantioselective hydrogenation, cross-coupling, and addition reactions.
• Pharmaceutical Intermediates: A key chiral scaffold in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system, cardiovascular, and oncological diseases.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: A monomer or dopant for creating chiral polymers, liquid crystals, and advanced optical materials with specific helical structures.
• Chiral Resolution: Employed as a chiral selector or stationary phase modifier in chromatography for the separation of enantiomers.
• Academic & Process R&D: A valuable tool for exploring new methodologies in stereochemistry and scaling up chiral processes.

Basic Information

Product Name	(R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl
CAS No.	389867-61-2
Molecular Formula	C24H22Br2O4
Molecular Weight	534.24 g/mol
Synonyms	(R)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene; (R)-(+)-6,6'-Dibromo-BINOL MOM ether; (R)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; (R)-6,6'-Dibromo-2,2'-di(methoxymethoxy)-1,1'-binaphthyl; (R)-BINOL-6,6'-dibromo-2,2'-dimethyl ether MOM; 1,1'-Binaphthalene-2,2'-diol, 6,6'-dibromo-, 2,2'-bis(methoxymethyl) ether, (R)-; (R)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)binaphthyl
EINECS	Contact for details

Quality Control

Our (R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to ensure long-term stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.