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R-3-Iodo-2,2'-Bis(Methoxymethoxy)1,1'-Binaphthalene CAS NO 389125-79-5


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CAS No.:389125-79-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

R-3-Iodo-2,2'-Bis(Methoxymethoxy)1,1'-Binaphthalene is a sophisticated chiral binaphthyl derivative, serving as a key synthetic intermediate and ligand precursor in advanced organic chemistry. Its value lies in its functionalized structure, which is pivotal for constructing complex molecular architectures with high stereochemical control. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel catalysts and active pharmaceutical ingredients (APIs).

Application

  • As a versatile chiral building block in the asymmetric synthesis of pharmaceuticals and natural products.
  • Precursor for the synthesis of novel axially chiral ligands used in transition metal catalysis (e.g., for cross-coupling reactions).
  • Intermediate in the development of organic electronic materials and liquid crystals due to the rigid binaphthyl core.
  • Key starting material for preparing molecular sensors and probes where the iodine moiety allows for further functionalization.
  • Use in academic and industrial R&D for exploring new methodologies in stereoselective synthesis.

Basic Information

Product Name R-3-Iodo-2,2'-Bis(Methoxymethoxy)1,1'-Binaphthalene
CAS No. 389125-79-5
Molecular Formula C24H21IO4
Molecular Weight 500.22 g/mol
Synonyms (R)-3-Iodo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene; (R)-3-Iodo-2,2'-bis(MOM)-1,1'-binaphthyl; (R)-3-I-BINOL-Bis(MOM) ether; (R)-3-Iodo-2,2'-di(methoxymethoxy)-1,1'-binaphthyl; 1,1'-Binaphthalene, 3-iodo-2,2'-bis(methoxymethoxy)-, (R)-; R-3-I-BINOL(MOM)2; (R)-3-Iodo-BINOL bis(methoxymethyl) ether
EINECS Contact for details

Quality Control

Every batch of R-3-Iodo-2,2'-Bis(Methoxymethoxy)1,1'-Binaphthalene is produced and tested under strict quality management protocols to ensure high chemical purity and enantiomeric excess. Our standard quality commitment includes comprehensive analytical verification via HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with each shipment to support your R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC/IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Melting Point Contact for details
Heavy Metals < 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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