Description

(R,R)-n-Benzyl-3,4-trans-Dimesolate Pyrrolidine is a high-purity chiral building block and organocatalyst of significant synthetic utility. Its defined stereochemistry makes it a valuable intermediate for the asymmetric synthesis of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the fine chemical, agrochemical, and advanced material sectors seeking to introduce specific chiral motifs with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for neurological and cardiovascular targets.
• Asymmetric Organocatalysis: Employed as a catalyst or catalyst precursor in enantioselective organic transformations, such as Michael additions or aldol reactions.
• Ligand Synthesis: Used for the preparation of chiral ligands for transition metal catalysis, enhancing selectivity in hydrogenation and cross-coupling reactions.
• Fine Chemical Synthesis: Serves as a building block for creating complex, optically active molecules in custom synthesis and process development.
• Agrochemical Research: Applied in the development of novel, stereospecific pesticides and herbicides where biological activity is chirality-dependent.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry and for exploring new asymmetric synthetic pathways.

Basic Information

Product Name	(R,R)-n-Benzyl-3,4-trans-Dimesolate Pyrrolidine
CAS No.	380357-38-0
Molecular Formula	C20H24N2O6S2
Molecular Weight	452.54 g/mol
Synonyms	(2R,3R)-1-Benzyl-2,3-bis(methanesulfonyloxy)pyrrolidine; (R,R)-1-Benzyl-2,3-dimesyloxypyrrolidine; (R,R)-1-Benzyl-2,3-bis(methylsulfonyloxy)pyrrolidine; (2R,3R)-1-Benzylpyrrolidine-2,3-diyl dimethanesulfonate; (R,R)-N-Benzyl-2,3-dihydroxypyrrolidine dimesylate; Pyrrolidine, 1-benzyl-2,3-bis(methylsulfonyloxy)-, (2R,3R)-; (R,R)-N-Bn-2,3-dimesyloxypyrrolidine
EINECS	Contact for details

Quality Control

Our (R,R)-n-Benzyl-3,4-trans-Dimesolate Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.