Description

4-Fluoro-3-Formylphenylboronic Acid is a versatile bifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl group and a boronic acid moiety on a fluorinated aromatic ring, enables its use in sophisticated cross-coupling and subsequent functionalization reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly through Suzuki-Miyaura cross-coupling reactions to create biaryl structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require fluorinated aromatic components.
• Material Science Research: Serves as a monomer or linker for constructing novel organic frameworks, polymers, and liquid crystals with specific electronic properties.
• Chemical Biology & Probe Development: Utilized in creating fluorescent probes, sensors, and affinity ligands that target biological systems.
• Catalyst Ligand Preparation: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Product Name	4-Fluoro-3-Formylphenylboronic Acid
CAS No.	374538-01-9
Molecular Formula	C7H6BFO3
Molecular Weight	167.93 g/mol
Synonyms	(4-Fluoro-3-formylphenyl)boronic acid; 3-Formyl-4-fluorobenzeneboronic acid; 4-Fluoro-3-formylbenzeneboronic acid; 4-Fluoro-3-carboxybenzaldehyde boronic acid; Boronic acid, B-(4-fluoro-3-formylphenyl)-; 374538-01-9; 4-Fluoro-3-formyl phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.