Description

Pmpa Sodium Salt CAS NO 373645-42-2 is the sodium salt form of the potent nucleotide analog PMPA, a well-characterized reverse transcriptase inhibitor. This compound is a critical intermediate and active pharmaceutical ingredient (API) in the research and development of antiviral therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on virology and drug discovery for the treatment of viral infections.

Application

• Antiviral Drug Intermediate: Serves as a key building block in the synthesis of nucleotide-based antiviral medications.
• Biochemical Research: Used as a reference standard and tool compound in studies of viral replication mechanisms, particularly for HIV and other retroviruses.
• Pharmaceutical Development: Employed in the formulation and preclinical development of new antiviral therapies targeting reverse transcriptase.
• Active Pharmaceutical Ingredient (API): Functions as the core active component in the manufacture of investigational antiviral drugs.

Basic Information

Product Name	Pmpa Sodium Salt
CAS No.	373645-42-2
Molecular Formula	C8H13N5NaO5P
Molecular Weight	313.18 g/mol
Synonyms	(R)-9-(2-Phosphonomethoxypropyl)adenine Sodium Salt; PMPA Sodium Salt; (R)-PMPA Na Salt; GS-9148 (Sodium Salt); Tenofovir Precursor Sodium Salt; (R)-PMPA monosodium salt; (2R)-9-[2-(Phosphonomethoxy)propyl]adenine Sodium Salt; Adefovir Related Compound
EINECS	Contact for details

Quality Control

Our Pmpa Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.