Description

2,4-Difluoro-5-Methylbenzoic Acid is a high-value fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic placement of fluorine atoms and a methyl group on the aromatic ring, which allows for precise modulation of electronic properties, lipophilicity, and metabolic stability in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl benzoate structure contributes to improved biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays, leveraging its ability to influence molecular polarity and alignment.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials for applications in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for introducing a difluoromethyl-substituted benzoic acid moiety into complex molecules during medicinal chemistry and material science exploration.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes for proprietary compounds.

Basic Information

Product Name	2,4-Difluoro-5-Methylbenzoic Acid
CAS No.	367954-99-2
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	5-Methyl-2,4-difluorobenzoic Acid; 2,4-Difluoro-5-methylbenzoic Acid; Benzoic acid, 2,4-difluoro-5-methyl-; 367954-99-2; 2,4-Difluoro-5-methyl-benzoic acid; 5-Methyl-2,4-difluorobenzoic acid; 2,4-Difluoro-5-methylbenzoicacid
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Methylbenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.