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n-(9-Anthracenemethyl)Cinchoniumbromide CAS NO 365567-24-4


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CAS No.:365567-24-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(9-Anthracenemethyl)Cinchoniumbromide is a specialized organocatalyst and chiral phase-transfer catalyst derived from cinchona alkaloids. This compound is valued for its ability to induce high enantioselectivity in asymmetric synthesis, a critical factor in producing optically pure pharmaceutical intermediates and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

  • Asymmetric Synthesis: Employed as a chiral phase-transfer catalyst (PTC) for enantioselective alkylation, Michael addition, and other C-C bond-forming reactions.
  • Pharmaceutical Intermediates: Key in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
  • Agrochemical Production: Used in the development of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
  • Academic & Industrial R&D: A vital tool for methodological development in organic chemistry laboratories for exploring new asymmetric transformations.
  • Fine Chemical Manufacturing: Facilitates the production of high-value chiral compounds used in flavors, fragrances, and electronic chemicals.
  • Material Science: Potential applications in the synthesis of chiral polymers and liquid crystals for advanced optical materials.

Basic Information

Product Name n-(9-Anthracenemethyl)Cinchoniumbromide
CAS No. 365567-24-4
Molecular Formula C₃₆H₃₅BrN₂O
Molecular Weight 567.58 g/mol
Synonyms N-[(9-Anthracenyl)methyl]cinchoninium bromide; (9-Anthrylmethyl)cinchoninium bromide; Cinchoninium, N-(9-anthrylmethyl)-, bromide; Cinchona Alkaloid-Derived Phase Transfer Catalyst; Anthracenylmethylcinchoninium Bromide; Asymmetric Phase Transfer Catalyst; PTC-Cinchona Anthracenyl Derivative; 9-Anthracenemethyl Cinchoninium Bromide
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Quality Control

Our n-(9-Anthracenemethyl)Cinchoniumbromide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure consistent performance and high enantiomeric excess (ee). A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and residual solvents is supplied with every order, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain catalytic activity.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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