Description

4'-Chloro-4-Biphenylboronic Acid is a high-purity organoboron compound, a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted biphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific chlorinated biaryl motifs.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and in the development of new catalytic systems.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for constructing complex organic molecules via palladium-catalyzed cross-coupling.
• Liquid Crystal and Polymer Chemistry: Used as a synthetic intermediate for compounds with potential application in liquid crystal displays and high-performance polymers.

Basic Information

Item	Details
Product Name	4'-Chloro-4-Biphenylboronic Acid
CAS No.	364044-44-0
Molecular Formula	C12H10BClO2
Molecular Weight	232.47 g/mol
Synonyms	4-Chloro-4'-biphenylboronic Acid; (4'-Chloro[1,1'-biphenyl]-4-yl)boronic Acid; [1,1'-Biphenyl]-4-boronic Acid, 4'-Chloro-; p-Chlorobiphenyl-4-boronic Acid; 4-(4-Chlorophenyl)phenylboronic Acid; 4'-Chloro-1,1'-biphenyl-4-boronic Acid; 4-Chloro-4'-biphenylboronic Acid Pinacol Ester (common derivative)
EINECS	Contact for details

Quality Control

Our 4'-Chloro-4-Biphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.