Description

[(1S)-2-[(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]Hex-2-Yl]-1-(3-Hydroxytricyclo[3.3.1.13,7]Dec-1-Yl)-2-Oxoethyl]-1,1-Dimethylethyl Ester Carbamic Acid is a sophisticated, high-purity chemical intermediate characterized by its complex, multi-cyclic molecular architecture. This compound is of significant commercial interest due to its role as a key building block in the synthesis of advanced pharmaceutical agents, particularly those targeting complex biological pathways. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, including central nervous system (CNS) drugs and enzyme inhibitors. The structural complexity of this molecule necessitates a supply chain partner with expertise in handling sensitive, high-value intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary active pharmaceutical ingredients (APIs), especially for neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for candidate drugs during clinical development phases.
• Bioconjugation & Prodrug Synthesis: Its functional groups make it suitable for creating targeted drug delivery systems or prodrug formulations to enhance bioavailability.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and cellular signaling pathways.

Basic Information

Product Name	[(1S)-2-[(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]Hex-2-Yl]-1-(3-Hydroxytricyclo[3.3.1.13,7]Dec-1-Yl)-2-Oxoethyl]-1,1-Dimethylethyl Ester Carbamic Acid
CAS No.	361442-01-5
Molecular Formula	C22H31N3O5
Molecular Weight	417.50 g/mol
Synonyms	Carbamic acid, N-[(1S)-2-[(1S,3S,5S)-3-(aminocarbonyl)-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester; tert-Butyl (1S)-2-[(1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexan-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethylcarbamate; 361442-01-5; Bicyclo[3.1.0]hexane-2-carboxamide derivative; Adamantanol carbamate intermediate
EINECS	Contact for details

Quality Control

Our [(1S)-2-[(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]Hex-2-Yl]-1-(3-Hydroxytricyclo[3.3.1.13,7]Dec-1-Yl)-2-Oxoethyl]-1,1-Dimethylethyl Ester Carbamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification and impurity profiling to ensure it meets the exacting standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.