Description

(R)-(+)-1-((R)-2-(Diphenylphosphino)Ferrocenyl)Ethyldicyclohexylphosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its value lies in its ability to induce exceptional enantioselectivity and catalytic activity in transition metal-catalyzed reactions, enabling the efficient synthesis of single-enantiomer compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for creating advanced intermediates and active ingredients.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, enamines, and ketones, critical for producing chiral pharmaceutical building blocks.
• Asymmetric Cross-Coupling Reactions: Facilitates C-C and C-X bond-forming reactions with high stereocontrol, such as Suzuki-Miyaura and Buchwald-Hartwig aminations.
• Pharmaceutical Intermediate Synthesis: Enables the production of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and pesticides where the biological activity is often specific to one enantiomer.
• Fine Chemical and Fragrance Production: Applied in the creation of high-value chiral flavors, fragrances, and specialty materials.
• Academic and Industrial R&D: A vital tool for methodology development in organic synthesis and catalysis research within university and corporate laboratories.

Basic Information

Product Name	(R)-(+)-1-((R)-2-(Diphenylphosphino)Ferrocenyl)Ethyldicyclohexylphosphine
CAS No.	360048-66-4
Molecular Formula	C36H42FeP2
Molecular Weight	592.49 g/mol
Synonyms	(R,R)-JOSIPHOS; (R)-(+)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine; (R)-1-((S)-2-(Diphenylphosphino)ferrocenyl)ethyldicyclohexylphosphine; Josiphos SL-J009-1; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine; J009-1; (R,R)-JOSIPHOS ligand; Chiral Josiphos ligand
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-((R)-2-(Diphenylphosphino)Ferrocenyl)Ethyldicyclohexylphosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.