Description

n-Boc-β-Alanine-β-Methyl-n-Carboxyanhydride is a specialized, high-purity building block used in advanced organic synthesis. This compound matters as a key intermediate for the controlled introduction of β-amino acid derivatives, enabling the synthesis of complex peptides and peptidomimetics with enhanced stability. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and bioactive molecules.

Application

• Peptide Synthesis: As a key monomer for the solid-phase or solution-phase synthesis of peptides containing β-amino acid residues.
• Pharmaceutical Intermediates: For the production of active pharmaceutical ingredients (APIs) and drug candidates targeting various diseases.
• Bioconjugation: In the development of peptide-drug conjugates and other bioconjugates for targeted drug delivery systems.
• Protease Inhibitor Development: Serving as a core scaffold for creating inhibitors of specific proteolytic enzymes.
• Material Science: For the synthesis of novel polymers and biomaterials with tailored degradation profiles and mechanical properties.
• Chemical Biology Research: As a tool compound for studying protein-protein interactions and cellular signaling pathways.

Basic Information

Product Name	n-Boc-β-Alanine-β-Methyl-n-Carboxyanhydride
CAS No.	357610-31-2
Molecular Formula	C10H15NO5
Molecular Weight	229.23 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-2-methylpropanoic acid N-carboxyanhydride; Boc-β-Ala(Me)-NCA; Boc-β-Alanine-β-methyl-N-carboxyanhydride; tert-Butyl (1-((2-methyl-5-oxooxazol-4(5H)-ylidene)amino)-1-oxopropan-2-yl)carbamate; N-Boc-3-amino-2-methylpropionic acid NCA; N-Boc-β-Alanine-β-methyl-NCA; 2-Methyl-3-[(tert-butoxycarbonyl)amino]propanoic acid 2,5-dioxooxazolidin-4-yl ester
EINECS	Contact for details

Quality Control

Our n-Boc-β-Alanine-β-Methyl-n-Carboxyanhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture uptake and decomposition. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (DMF, DCM, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.