Description

5-(2-Fluorophenyl)-Furan-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, combining a furan carboxylic acid core with a fluorinated aromatic ring, provides a versatile scaffold for creating novel molecules with targeted properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom can enhance bioavailability and environmental stability.
• Material Science: Acts as a monomer or functionalizing agent for creating specialized polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology: Employed as a probe or tag in biochemical research due to the spectroscopic handle provided by the fluorine atom and furan ring.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, such as Suzuki or Sonogashira couplings, to construct complex polycyclic aromatic systems for various applications.

Basic Information

Product Name	5-(2-Fluorophenyl)-Furan-2-Carboxylic Acid
CAS No.	353761-02-1
Molecular Formula	C11H7FO3
Molecular Weight	206.17 g/mol
Synonyms	2-Furoic acid, 5-(2-fluorophenyl)-; 5-(2-Fluorophenyl)-2-furancarboxylic acid; 2-Fluorophenylfuran-2-carboxylic Acid; 5-(o-Fluorophenyl)furan-2-carboxylic acid; Furan-2-carboxylic acid, 5-(2-fluorophenyl)-; 353761-02-1; 5-(2-Fluorophenyl)furan-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)-Furan-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, ensure containers are clearly labeled and stored on appropriate secondary containment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.