Description

3-Bromo-2-Fluorophenylboronic Acid is a high-purity organoboron compound, specifically a halogenated phenylboronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for methodology development and library synthesis in medicinal chemistry.
• Ligand Precursor: Can be utilized to synthesize sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	3-Bromo-2-Fluorophenylboronic Acid
CAS No.	352535-97-8
Molecular Formula	C6H5BBrFO2
Molecular Weight	218.82 g/mol
Synonyms	(3-Bromo-2-fluorophenyl)boronic acid; 2-Fluoro-3-bromophenylboronic acid; 3-Bromo-2-fluorobenzeneboronic acid; Boronic acid, B-(3-bromo-2-fluorophenyl)-; 352535-97-8; 3-Br-2-F-C6H3B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.