Description

Methyllycaconitine (Citrate) CAS NO 351344-10-0 is a high-purity, citrate salt form of the potent and selective α7 nicotinic acetylcholine receptor (nAChR) antagonist. This compound is of significant value in neuroscience and pharmacological research for its ability to selectively block specific neuronal pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and chemical suppliers serving the life sciences sector for use in receptor characterization, neuropharmacology studies, and the development of novel therapeutic agents.

Application

• Neuroscience Research: As a selective antagonist for studying the function and distribution of α7 nicotinic acetylcholine receptors in the central nervous system.
• Pharmacological Profiling: Used in in vitro and in vivo assays to investigate receptor-ligand interactions and signal transduction mechanisms.
• Drug Discovery & Development: A critical reference standard and tool compound in the screening and development of new therapeutics targeting nAChRs for conditions like cognitive disorders and pain.
• Biochemical Reagent: Employed in the preparation of experimental buffers and solutions for electrophysiology and binding studies.
• Toxicology Studies: Used to model and understand the effects of specific neurotoxins and to develop potential antidotes.
• Academic & Institutional Research: A key reagent for universities and government labs conducting fundamental research on cholinergic systems.

Basic Information

Product Name	Methyllycaconitine (Citrate)
CAS No.	351344-10-0
Molecular Formula	C37H50N2O10 • xC6H8O7
Molecular Weight	Contact for details
Synonyms	MLA Citrate; Methyllycaconitine citrate salt; (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxyaconitane-4,8,9-triol 4-benzoate 8-acetate 9-veratrate citrate; 16β-Methyllycaconitine citrate; α7 nAChR antagonist (MLA); Aconitine, methyllycaconitine, citrate
EINECS	Contact for details

Quality Control

Our Methyllycaconitine (Citrate) is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥95%
Purity (HPLC)	≥98%
Water Content (KF)	≤5.0%
Residue on Ignition	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.