Description

R-2,2'-Dihydroxy-[1,1'-Binaphthalene]-3-Carboxaldehyde is a chiral binaphthyl derivative that serves as a sophisticated building block and ligand precursor in advanced organic synthesis. Its value lies in its rigid, axially chiral structure, which is essential for inducing stereoselectivity in catalytic and synthetic processes. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing enantiomerically pure products and novel materials.

Application

• Asymmetric Synthesis Ligand: A key precursor for synthesizing chiral phosphine, amine, and N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Pharmaceutical Intermediates: Employed in the research and development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Chiral Stationary Phases (CSPs): Used in the development and manufacture of high-performance liquid chromatography (HPLC) columns for the separation of enantiomers.
• Molecular Recognition: Serves as a core structural unit in the design of chiral sensors, receptors, and supramolecular hosts for analytical and diagnostic applications.
• Advanced Material Science: A building block for creating chiral polymers, liquid crystals, and organic frameworks with unique optical and electronic properties.
• Agrochemical Research: Utilized in the synthesis of chiral herbicides, fungicides, and plant growth regulators to enhance efficacy and reduce environmental impact.

Basic Information

Product Name	R-2,2'-Dihydroxy-[1,1'-Binaphthalene]-3-Carboxaldehyde
CAS No.	349149-08-2
Molecular Formula	C21H14O3
Molecular Weight	314.33 g/mol
Synonyms	(R)-3-Formyl-2,2'-dihydroxy-1,1'-binaphthyl; (R)-2,2'-Dihydroxy-1,1'-binaphthalene-3-carboxaldehyde; (R)-BINOL-3-carboxaldehyde; (R)-3-Carboxyaldehyde-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3-CHO-BINOL; (R)-3-Formyl-BINOL; (R)-BINOL-3-CHO; (R)-2,2'-Dihydroxy-[1,1'-binaphthalene]-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our R-2,2'-Dihydroxy-[1,1'-Binaphthalene]-3-Carboxaldehyde is produced under strict quality management protocols to ensure high chemical purity and chiral integrity. Each batch is characterized by advanced analytical techniques, including HPLC for chiral purity and assay, NMR for structural confirmation, and optical rotation measurement. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen in a freezer (-20°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.