Description

5-(2-Fluorophenyl)-1,3-Oxazole-4-Carboxylicacid is a high-purity fluorinated oxazole derivative, a key heterocyclic building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a fluorinated aromatic ring with a carboxylic acid-functionalized oxazole core, enabling precise modifications in target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorophenyl-oxazole moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals, organic semiconductors, and advanced polymers with tailored electronic properties.
• Chemical Biology & Probe Development: Employed in the synthesis of fluorescent probes, enzyme inhibitors, and other molecular tools for biochemical and diagnostic research applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for client projects.

Basic Information

Product Name	5-(2-Fluorophenyl)-1,3-Oxazole-4-Carboxylicacid
CAS No.	347187-18-2
Molecular Formula	C10H6FNO3
Molecular Weight	207.16 g/mol
Synonyms	5-(2-Fluorophenyl)-1,3-oxazole-4-carboxylic acid; 4-Oxazolecarboxylic acid, 5-(2-fluorophenyl)-; 5-(2-Fluorophenyl)-4-oxazolecarboxylic acid; 5-(2-Fluorophenyl)oxazole-4-carboxylic acid; 2-Fluoro-5-(4-carboxyoxazol-5-yl)benzene; 347187-18-2; 5-(o-Fluorophenyl)-1,3-oxazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Fluorophenyl)-1,3-Oxazole-4-Carboxylicacid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.