Description

Methyl 2-Bromomethyl-3-Trifluoromethyl Benzoate is a high-value, multi-functional chemical intermediate featuring both bromomethyl and trifluoromethyl substituents on an aromatic ester core. This compound is strategically important for introducing these key functional groups into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those requiring trifluoromethyl groups to enhance metabolic stability, lipophilicity, and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group often contributes to improved biological activity and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of monomers and polymers with unique electronic or surface properties for advanced material applications.
• Fluorine Chemistry: An essential reagent for introducing fluorine atoms into organic molecules, a critical step in modern medicinal and agrochemical discovery.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 2-Bromomethyl-3-Trifluoromethyl Benzoate
CAS No.	346603-68-7
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	Methyl 2-(Bromomethyl)-3-(trifluoromethyl)benzoate; Benzoic acid, 2-(bromomethyl)-3-(trifluoromethyl)-, methyl ester; 2-Bromomethyl-3-trifluoromethylbenzoic acid methyl ester; Methyl α-bromo-3-(trifluoromethyl)ortho-toluate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromomethyl-3-Trifluoromethyl Benzoate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and consistency to meet the stringent requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with each shipment to guarantee reliable performance in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature of the compound, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.