Description

Methyl 2-Methyl-3-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its core value lies in the strategic incorporation of the trifluoromethyl group, which is highly sought after for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display technologies, improving dielectric anisotropy and stability.
• Advanced Polymer Modifiers: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and altered refractive indices.
• Organic Synthesis & Catalysis Research: A valuable reagent in academic and industrial R&D for studying fluorination effects and developing new catalytic methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring specific, high-value fluorinated aromatic intermediates.

Basic Information

Item	Detail
Product Name	Methyl 2-Methyl-3-(Trifluoromethyl)Benzoate
CAS No.	346603-63-2
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	2-Methyl-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 2-methyl-3-(trifluoromethyl)benzoate; 3-(Trifluoromethyl)-o-toluic acid methyl ester; Methyl 3-trifluoromethyl-2-methylbenzoate; Benzoic acid, 2-methyl-3-(trifluoromethyl)-, methyl ester; 346603-63-2; Methyl 2-methyl-3-trifluoromethylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Methyl-3-(Trifluoromethyl)Benzoate adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR, IR, and GC-MS. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, ensuring compliance with your specific R&D or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. The container must be kept tightly closed in a dry and inert atmosphere to preserve quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.