Description

(1R,2R)-N,N''-Bis-Boc-Cyclohexane-1,2-Diamine is a high-purity, chiral diamine derivative featuring two tert-butoxycarbonyl (Boc) protecting groups. This compound is a critical chiral building block and ligand for asymmetric synthesis, valued for its role in constructing complex molecular architectures with high stereochemical fidelity. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for developing active pharmaceutical ingredients (APIs), catalysts, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Catalyst & Ligand Synthesis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for activity.
• Peptidomimetics & Molecular Scaffolds: Employed in medicinal chemistry to create conformationally restricted peptide analogs and novel molecular scaffolds.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing chiral polymers and advanced materials with specific optical properties.
• Academic & Process R&D: A valuable reagent for method development and scale-up studies in asymmetric synthesis and process chemistry.

Basic Information

Product Name	(1R,2R)-N,N''-Bis-Boc-Cyclohexane-1,2-Diamine
CAS No.	345905-88-6
Molecular Formula	C₁₈H₃₄N₂O₄
Molecular Weight	342.48 g/mol
Synonyms	(1R,2R)-1,2-Bis[(tert-butoxycarbonyl)amino]cyclohexane; (1R,2R)-1,2-Diaminocyclohexane N,N'-di-Boc; (1R,2R)-Cyclohexane-1,2-diamine, N,N'-bis[(1,1-dimethylethoxy)carbonyl]-; (1R,2R)-Boc-DACH; (1R,2R)-N,N'-Di-Boc-1,2-diaminocyclohexane; (1R,2R)-trans-N,N'-Di-Boc-1,2-diaminocyclohexane; (1R,2R)-1,2-Diaminocyclohexane di-Boc derivative
EINECS	Contact for details

Quality Control

Our (1R,2R)-N,N''-Bis-Boc-Cyclohexane-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and commercial use. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.