Description

2-Chloro-4-Trifluoromethoxybenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, particularly in the development of active pharmaceutical ingredients (APIs) with trifluoromethoxy and chloro substituents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated aryl motifs.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors, where its structure can tune electronic properties.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating bespoke chemical libraries.
• Liquid Crystal and Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and liquid crystalline materials.

Basic Information

Item	Details
Product Name	2-Chloro-4-Trifluoromethoxybenzeneboronic Acid
CAS No.	345226-20-2
Molecular Formula	C7H5BClF3O3
Molecular Weight	239.38 g/mol
Synonyms	2-Chloro-4-(trifluoromethoxy)benzeneboronic Acid; (2-Chloro-4-(trifluoromethoxy)phenyl)boronic Acid; 2-Chloro-α,α,α-trifluoro-p-anisoleboronic Acid; Boronic acid, B-[2-chloro-4-(trifluoromethoxy)phenyl]-; 345226-20-2; 2-Chloro-4-trifluoromethoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Trifluoromethoxybenzeneboronic Acid is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR, and MS to verify identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure it meets your precise research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.