Description

(S)-(+)-tert-Butylsulfinamide CAS NO 343388-28-3 is a high-purity chiral sulfinamide reagent, a cornerstone in modern asymmetric synthesis. Its primary value lies in its exceptional performance as a chiral auxiliary and ligand, enabling the stereoselective construction of complex molecules with high enantiomeric purity. This compound is critically needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for the production of active pharmaceutical ingredients (APIs), advanced intermediates, and novel materials.

Application

• As a versatile chiral auxiliary in the asymmetric synthesis of amines, amino acids, and amino alcohols via sulfinimine chemistry.
• As a key ligand or precursor for catalyst systems in enantioselective metal-catalyzed transformations.
• In the research and development of pharmaceutical intermediates and Active Pharmaceutical Ingredients (APIs) requiring high stereochemical fidelity.
• For the synthesis of agrochemicals and other bioactive compounds where chirality is crucial for efficacy.
• In the preparation of fine chemicals and specialty materials with defined stereochemistry.
• As a critical reagent in academic and industrial R&D for methodological development in organic synthesis.

Basic Information

Product Name	(S)-(+)-tert-Butylsulfinamide
CAS No.	343388-28-3
Molecular Formula	C4H11NOS
Molecular Weight	121.20 g/mol
Synonyms	(S)-tert-Butanesulfinamide; (S)-2-Methyl-2-propanesulfinamide; (S)-(+)-2-Methylpropane-2-sulfinamide; (S)-tert-Butylsulfinylamine; (S)-t-Butylsulfinamide; (S)-tert-Butylsulfinylamide; tert-Butylsulfinamide (S enantiomer); (S)-TBSA
EINECS	Contact for details

Quality Control

Our (S)-(+)-tert-Butylsulfinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.